Prof Karine Clément is full professor of Nutrition, Division of Cardiometabolism, Pitié Salpêtrière hospital and at Paris 6 Pierre et Marie Curie university in Paris. KC has been involved in genetic aspects of human obesity. Her work led to the identification of monogenic forms of obesity (Leptin receptor and MC4R mutations) and to several genetic risk factors in common obesity. She contributed to more than 200 international publications, reviews and many international conferences in the field. She performed a post-doctoral fellowship at Stanford University, CA, USA where she acquired competencies in gene profiling approaches applied to complex diseases (1999-2000). In 2001 she obtained a young INSERM “Avenir” team focused on the characterization of patterns of gene expression induced by environmental perturbations. Her group showed notably that inflammatory and remodeling genes in human adipose tissue are modulated by weight variation in parallel to macrophage infiltration changes.
Since January 2006, she is director of the INSERM team Nutrition and obesity (Nutri0mique) and joined in 2007 the Cordelier Research Center (www.crc.jussieu.fr). She is a member and expert of several national and international scientific committees in obesity and metabolism and contributes to several European Networks in genetics and functional genomics (Diogenes, Hepadip, ADAPT, FLIP and recently METACARDIS). Since 2011, she is director of the Center of Excellence ICAN Institute de CardiometAbolism and Nutrition, dedicated to innovative Care, Research and training in the field of Cardiology and metabolic diseases.