Dr Francis Finucane

Francis Finucane qualified from RCSI in Dublin and completed physician training in Beaumont Hospital, obtaining the MRCPI in 2001.  He continued clinical training in endocrinology, diabetes mellitus and general internal medicine in Dublin, including a period of clinical research at the Metabolic Research Unit in St. James’ Hospital under the supervision of Prof. John Nolan.  There, he conducted detailed metabolic assessments of young people with obesity, insulin resistance and type 2 diabetes and was awarded an MD from the University of Dublin (TCD) in 2008 for this work.  In order to explore further the mechanistic basis for the association between insulin resistance and adiposity, he undertook a four year period of post-doctoral research at the MRC Epidemiology Unit in the Institute of Metabolic Science in Cambridge, supervised by Prof. Nick Wareham and Dr. Simon Griffin and funded by travel grants from Irish training bodies and then an MRC Career Development Fellowship. 

Building on his work in Dublin, he conducted a formal assessment of the effects of aerobic exercise in older people and different factors modulating the response to an aerobic exercise intervention.  He published the first study to show that exercise reduces liver fat content in humans.  He led the writing group on a major international collaboration describing a novel genetic polymorphism associated with reduced body fat but increased diabetes and cardiovascular risk (IRS1).  Since returning to Ireland in 2010, Dr. Finucane has led the development of clinical services for people with severe obesity and related metabolic disorders from the West of Ireland.  He is a principal investigator with Molecular Medicine Ireland and is an honorary senior lecturer in medicine at NUI Galway.